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KMID : 0363019890190010063
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Journal of Korean Academy of Periodontology
1989 Volume.19 No. 1 p.63 ~ p.70
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Clinical trial of unsaponifiable fraction of zea mays L. on healing after surgical periodontal therapy in human
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Choi Sang-Mook
Han Soo-Boo
Hwang Kwang-Sei
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Abstract
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The efficacy of unsaponifiable fraction of Zea Mays L compared with placebo was evaluated by a double blind method. Subjects were 57 SNUDH out-patients undergoing the Modified Widman flap surgery. The subjects were divided randomly into 2 groups ; 36 subjects were given sugar -coated tablets containing 35mg active drug and 21 were given only placebo sugar-coated tablets. To evaluate the effect, we used a gingival index, pocket depth measurement, a tooth mobility index and the rate of lamina dura appearance. The subjects were evaluated before surgery, 2 weeks, 4 weeks, 8 weeks and 12 weeks after surgery. Zea Mays L seemed to play a significant role in the reduction of gingival inflammation after surgery and was superior to placebo in all parameters and had little adverse effect.
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KEYWORD
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